Some, are reveling in new momentum, while others, trying to figure out how to jumpstart faltering campaigns.
John McCain is the new Republican front-runner in a comeback that's re-shaped the Republican race.
"We certainly showed them what a come back is all about," said Senator John McCain (R) Arizona.
McCain did particularly well with moderates and independents; 43 percent compared to Mitt Romney's 26-percent.
Romney did better among conservatives and tonight Romney is counting on Michigan's primary to turn it around.
"I always thought that someday I would be in the car business, but now I think I can do more than the car business and help Michigan by becoming the next president," said former Massachusetts governor (R) Mitt Romney.
"Mitt Romney is on life support to use the cliché he's pulled all of his ads from South Carolina and Florida and put it all in Michigan a lot of money it's all there he knows he has to win Michigan," said Sam Donaldson from ABC News.
Sam Donaldson, who has covered presidential politics for decades, says Rudy Giuliani is also in trouble.
Giuliani is playing down his fourth place finish saying he didn't focus on New Hampshire.
"But here's a statistic for you he said I did spend that much attention here but yes he did. Next to Mitt Romney, Rudy Giuliani made the most visits of any Republican candidate to this state and he did so poorly," said Donaldson.
Mike Huckabee is turning to South Carolina, his southern roots and what he hopes will be a boost from a strong Evangelical base.
"We haven't seen anything but ice and snow for the past three weeks and it sure is good to get down to the south ladies and gentlemen," said former Arkansas governor (R) Mike Huckabee.
For Hillary Clinton the big factor in last night's win was women.
The numbers show a wide margin among women voters 47 to 34 percent for Barak Obama, and if you look at women above 65 the difference is enormous -- a 30-point advantage for Clinton.
"I've always considered myself kind of a servant leader and in this process over the last four days, I felt that I finally could convey that to people and that they heard me and that we connected in a real personal and profound feeling," said Senator Hillary Clinton (D) New York.
Barack Obama did well among the youngest voters 18-25. But the poll workers I talked to told me they didn't see a big surge of very young voters.
"Actually I'm seeing more people in my age, 70's in that bracket," said poll worker Bill Belanger.
For Barack Obama, a big factor is former senator John Edwards. Edwards spent today in South Carolina appealing to young voters at Clemson University.
Edwards claims South Carolina is home turf and is counting on doing well there.
The Obama campaign knows that as long as Edwards is in the race, he'll split the anti-Hillary Clinton vote -- however large or small that may be.
