The new center is located at the main post in the Presidio.
As goodwill ambassador for the United Nations Development Fund for Women, Kidman says the center will serve as a home for activists and world leaders to develop solutions to end violence against women and children.
"This is action, this is San Francisco showing what they can do and it's starting as you're right here -- the walls, the windows -- this is the place where it begins," she said. "And we have to make that vision stronger."
The group says by having a building in a public park, they're making a statement about their commitment to solving a public epidemic.