The church is located at 16th and Dolores Streets. Protesters say they are concerned about the potential long-term health risks from electromagnetic waves. So far, there is no scientific consensus that cell towers can cause negative health effects.
The church would receive up to $1,200 a month from the tower.
"The truth is we just don't know. We really don't know what the long-term effects are going to be, and to use our children as guinea pigs in this is not appropriate," protestor Jessica Ross told ABC7.
"I feel in order to protect the neighborhood, you've got to have communication. That's the main reason," said parishioner Walter Elliott.
T-Mobile responded by saying it is meeting the growing demand for wireless coverage and that a strong cell network is vital during emergencies.