Six Bay Area African-American clergy leaders will be part of the march taking place on Saturday.
The group held a send-off blessing on Thursday, where they vowed to stand together with the Latino community to fight what they say is an oppressive law.
"We don't need laws that separate us. We don't need laws that federalize out police forces, making all of our communities less safe. What we need to do is to come together and find reasonable solutions to very real problems," B.K. Woodson, Sr. from Bay Area Christian Connection said.
The clergy leaders say the law will increase racial profiling, which they say is already a major problem along the U.S.-Mexico border.