Police tell ABC7 the driver was targeting people on bicycles. The rampage ended when the driver crashed his car at 17th and Missouri Street and then took off running.
Witnesses say the suspect driver was headed westbound on 17th Street when he veered off and slammed into a parked SUV. He then backed up and struck a cyclist, then got out of his car and walked away.
That cyclist was taken away with what appears to be some broken bones and after the final crash, it is believed the suspect driver may be injured too.
Police believe the same driver struck other vehicles and cyclists at three other locations.
There were cyclists injured at Harrison Street and 24th Street, on the 2800 block of Harrison, and at Pennsylvania Avenue and 23rd Street.
Out of those four cyclists hit, three victims are at the hospital; one is in critical, one in serious, and one in fair condition. The fourth cyclist refused treatment.
Police say they have found the driver's wallet, so they should be able to identify the person they are looking for.
The suspect is still at large.