Police responded to reports of a disturbance in the 1200 block of Oxton Drive shortly after 3 a.m. and discovered a male victim who had been fatally shot.
The suspects had fled the scene before officers arrived and are still at large, police said.
A short time later, officers received reports that three gunshot victims walked into a hospital. One of the victims suffered non-life-threatening injuries. The other two victims are being treated and their condition was not immediately known.
Anyone with information regarding this incident is urged to call police at (408) 277-5283 or the anonymous tip line at (408) 947-7867 or http://svcrimestoppers.org/.
This incident marks San Jose's 25th homicide of the year.