The first sighting was around 7 p.m. near state Highway 92 just east of state Highway 35, emergency officials said.
About four hours later and less than 15 miles away around 11:15 p.m. a big cat was seen just east of Lindenbrook Road in Woodside.
Residents are advised to never approach a mountain lion.
Anyone who encounters a mountain lion should face the animal, make noise, and try to appear larger by waving arms and throwing rocks, emergency officials said. Small children should be picked up.
More information about mountain lions is available at www.keepmewild.org.