The pedestrian, a 49-year-old San Rafael resident, was crossing Second Street at G Street when he was hit by a Saab traveling eastbound on Second Street at about 9:35 p.m., according to the San Rafael Police Department.
The victim was pronounced dead at the scene.
The driver of the Saab, a San Rafael woman, had been returning home from a visit with family, police said.
She was not injured in the collision.
There was no indication that alcohol was a factor, police said.
The incident remains under investigation.