The iPad was stolen in May from a home in the 100 block of Danbury Lane, according to Redwood City police.
A GPS tracking app installed on the device called "Track Me Find Me" led police to an apartment building in the 1600 block of Oxford Street.
After an initial investigation, police were unable to find the stolen iPad or identify any suspects, Sgt. Sean Hart said.
On Saturday, however, the victim contacted police to say that recently taken photographs of a teenage girl and boy had automatically uploaded to his "iCloud" storage account.
Investigators were able to identify the 15-year-old girl and 16-year-old boy, and returned to the apartments at 1619 Oxford St., where the suspects were located and taken into custody, police said.
Police subsequently identified the pair as suspects in a second home burglary that occurred in the 300 block of Newcastle Drive on May 30.
Both have allegedly confessed to being involved in the two burglaries, according to police.
Police have not recovered the stolen property, Hart said. An undisclosed amount of cash was seized that is believed to have come from the sale of the items.