Gunshots were reported to police at 8:05 p.m. in the area of Ivy Drive and Windermere Avenue, police said.
Officers arrived at the scene to find four victims with gunshot wounds. The victims were transported to Stanford Hospital for medical treatment.
One victim is in critical condition, another victim is in serious condition, and two victims sustained minor injuries, according to Menlo Park police.
Two vehicles were witnessed fleeing the scene of the shooting. The vehicles were described as a black Honda and a black Acura. Both vehicles were seen heading northbound on Ivy Drive and have not been located.
Police have not identified any suspects or a motive for the shooting.
The incident remains under investigation and anyone with information regarding the shooting is asked to contact Menlo Park police at (650) 330-6300.