Three of the injured people are in critical condition, and one who was ejected from the Camaro is clinging to life, police Lt. Bisa French said.
The crash happened at 7:20 p.m. as the Camaro was traveling south on South 37th Street and collided with the truck heading north.
The truck flipped over and all of its three occupants were injured, one critically.
All four occupants of the Camaro were injured as well, including one female victim in grave condition tonight who was ejected from the Camaro.
The Camaro's driver was airlifted to a hospital in critical condition. The other two Camaro passengers' injuries were not life-threatening, French said.
French said that police are investigating reports that the Camaro was speeding and whether that contributed to the crash. Police are also investigating whether alcohol played a role.