Police said Juan Medrano Jr., 20, was driving his BMW on Richmond Parkway near Hilltop Drive around 3 p.m. when another car pulled up alongside his and someone inside shot him.
Medrano was airlifted to a hospital, where doctors later pronounced him brain-dead, placed him on life support and began harvesting his organs, Sgt. Nicole Abetkov said.
He was pronounced dead at 12:40 a.m. Saturday, a coroner's deputy said.
Police are still attempting to locate a passenger in the BMW who ran from the scene of the shooting.
Police are investigating the shooting as a possible gang-related crime, but no suspect information was available today, Abetkov said.
Anyone with information about this case is asked to call Richmond police Detective Hector Esparza at (510) 620-6655.