The shooting was reported on the first block of 14th Street around 7:10 p.m., according to Officer Albie Esparza.
Police located a female victim in her mid 20s who had been shot in her leg, Esparza said.
She was taken to a hospital, but her injuries were not considered life threatening.
Investigators believe the shooting occurred in connection with a robbery of a commercial establishment in the area, Esparza said.
Two suspects seen fleeing from the scene were described only as black male adults.
No arrests have been made.
Police are checking video surveillance and are asking any witnesses to contact them at (4150) 575-4444 or to text a tip to TIP411 with SFPD at the start of the message.
KGO contributed to this story