Bay Area technology aids in breast reconstruction

SAN FRANCISCO (KGO) -- When Chris Kyne faced a diagnosis of cancer in her left breast, she made an aggressive choice to get a double mastectomy, to be followed by breast reconstruction. Plastic surgeon, Kamakshi Zeidler, M.D., also told Chris about an experimental technology that might speed the time-table.

"We talked about the reconstruction and implants, and she introduced the idea to me of the AirXpanders," Kyne remembers.

The AirXpander is a temporary implant filled with compressed CO2 gas. It's placed under the skin during the mastectomy.

Later, the patient uses a wireless remote control, held over the breast area to slowly inflate the device over the course of several weeks. The purpose is to create a stretched out pouch, where surgeons will place the permanent breast implants during reconstruction. Dr. Zeidler says it's quicker and less painful than the saline injections traditionally used to expand the skin.

"Hearing that they're going to be in control of this expansion process to start and stop or go as quickly or as slowly as they want has a huge emotional impact. In addition, not having to come in and be poked by a needle when they're seeing their doctor," says Zeidler.

We first profiled AirXpanders several years ago while they were still in development. The company, based in Palo Alto, has now completed enrolment in a multi-year clinical trial. Preliminary data showed women with the AirXpanders completed expansion in an average of 17 days, compared to 52 days with saline injections.

"So you're able to give a lot more in a short period of time because the dose is made very, very small and comfortable for the patient," explains Zeidler.

Zeidler says the time frame for the reconstruction surgery still depends on the healing process which can vary, but that women using the AirXpanders will have their natural shape back, while doctors monitor their progress.

"Looking good in clothes, women can wear bathing suits with expanders and go about their regular lives," she adds.

Kyne completed breast reconstruction surgery, after participating in the AirXpander trial and believes the double mastectomy was the right decision for her.

"Because I'm 65 years old and I had places to go and things to do, and the rest of my life to live," says Kyne.

The company is now in the process of reviewing the final data from the study and plans to present it to the FDA for approval.

Written and produced by Tim Didion