And there are plenty of other exciting, surprising and cringe-worthy moments that people couldn't stop tweeting about.
The number one searched moment on social media was Leonardo DiCaprio's win for best actor.
The show's host, Chris Rock, dove right into the controversy surrounding this year's Oscars and the lack of diversity.
RELATED: Chris Rock comments on #Oscarssowhite during Oscars opening monologue
And #OscarsSoWhite was a trending hashtag for most of the night.
"Well, I'm here at the Academy Awards, otherwise known as the White People's Choice Awards. You realize if they nominated hosts, I wouldn't even get this job!" joked Chris Rock.
A beauty company is apologizing for a tweet mistaking Whoopi Goldberg for Oprah on the red carpet. Oprah's reaction was posted on Gayle King's Instagram.
"I feel pretty good if you're comparing me to Oprah. That's not a bad thing!" said Goldberg.
After DiCaprio's win, Lady Gaga's powerful performance was the second most searched topic. Her song featured sexual assault survivors, who joined her on stage. Vice President Joe Biden introduced her.
WATCH: Lady Gaga's Oscars performance
But it was Sam Smith who took home the Oscar for best original song.
"And he said that no openly gay man had every won an Oscar. And if this is the case or even if it isn't the case, I want to dedicate this to the LGBT community all around the world," said Smith.
Smith quickly found out that wasn't the case. Openly gay screenwriter Dustin Lance Black called him out on twitter and posted a video of when he won for Milk.
VIDEO: 2016 Oscar acceptance speeches
PHOTOS: 2016 Oscars Red Carpet fashion
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