Adam Wainwright became the National League's first nine-game winner, and the Cardinals beat Tampa Bay 1-0 on Tuesday night, the Rays' third straight shutout loss.
The Cardinals have three consecutive shutouts for the first time since April 2013. St. Louis, with 13 shutouts this season, was coming off 5-0 victories over Toronto on Saturday and Sunday.
"Our starting pitching has been extremely good these last few, to say the least," St. Louis manager Mike Matheny said.
It is the Cardinals' first stretch of three consecutive road shutouts since Sept. 29, 1962-April 10, 1963, when St. Louis had four in a row.
"Pretty amazing," said St. Louis slugger Matt Holliday, who homered.
Tampa Bay has been shut out an American League-leading 10 times this season. The Rays, who have lost 14 of 15, have not scored a run in a club-record 28 innings.
"It's kind of weird to watch because it just doesn't stay that negative for that long normally," Rays manager Joe Maddon said. "It just doesn't but it has. This is truly one of those anomaly moments where we've got to stick together as a group."
Wainwright (9-3) scattered seven hits over seven innings. Trevor Rosenthal got the final four outs, including a bases-loaded pop fly by Matt Joyce in the eighth, for his 17th save.
Holliday put the Cardinals up 1-0 with his fourth homer this season, a long drive to left center with two outs in the sixth off tough-luck loser Jake Odorizzi (2-7).
Holliday and Kolten Wong both returned to the Cardinals' lineup. Holliday was scratched Sunday due to a sore lower back, while Wong sat out three games with left shoulder soreness.
Holliday said his back is still a little stiff.
"Loosened up enough so I could get some good swings," he said.
Odorizzi, a Cardinals fan who grew up about 30 miles from Busch Stadium, had a strong performance in his first game against St. Louis. The right-hander gave up one run and three hits in a career-high 7 1/3 innings.
"Today I felt I was really executing my pitches and nothing they could do was going to beat me," Odorizzi said. "One mistake by me, and I got beat. It was the best outing I've ever had in the big leagues."
Odorizzi had allowed one baserunner, a fourth-inning walk to Holliday, before giving up consecutive two-out singles in the fifth to Jhonny Peralta and Jon Jay. The inning ended on a fly ball by Peter Bourjos.
The Rays threatened in both the first and fourth innings. Ben Zobrist hit a fly ball with two on to end the first. Logan Forsythe lined out to second with the bases loaded and two outs in the fourth.
"It's a tough lineup, it really is," Wainwright said. "They're going through a funk, I know. As soon as we leave town, they're going to break out. I've got a feeling."
Sam Freeman inherited two runners and then got two key outs in the eighth before Rosenthal replaced him.
Former Cardinals manager and Tampa native Tony La Russa will throw the ceremonial first pitch before the finale of the two-game interleague series Wednesday night. La Russa will be inducted into baseball's Hall of Fame on July 27. ... Tampa Bay C Ryan Hanigan (right hamstring tightness) will be activated from the 15-day DL on Wednesday. To make room on the roster, C Ali Solis was optioned to Triple-A Durham. ... The Rays signed 2014 first-round draft pick Casey Gillaspie, a first baseman out of Wichita State. ... St. Louis 1B Matt Adams (strained left calf) has started a rehab assignment with Triple-A Memphis. ... This was the third time that Tampa Bay C Jose Molina and his brother, Cardinals C Yadier Molina, played against each other in the majors. ... Rays LHP Erik Bedard (3-4) and St Louis RHP Michael Wacha (4-4) are Wednesday's scheduled starters.
Cardinals Shut Down Rays
Matt Holliday hit a home run for the game's only offense as the Cardinals defeated the Rays 1-0.