An instrumental player in Van Gaal's plans in Brazil, where the Dutch have been drawn in tricky Group B alongside Spain, Chile and Australia, Van Persie missed out two months towards the end of the Premier League season because of the injury suffered during Manchester United's win over Olympiakos in the round of 16 of the UEFA Champions League in March.
Although the player declared himself fit just a couple of days ago after being withdrawn at halftime in the Netherlands' warm-up game against Wales in Amsterdam, concerns remained and RVP himself admitted to some groin discomfort.
In a recent interview to Dutch newspaper "De Telegraaf", the Manchester United man said he had felt no twinges in the knee since the injury healed. "And that is several weeks now," added the player.
Another source of concern for the Netherlands seems to be Wesley Sneijder. The player complained of ankle pains during Saturday's practice and did not take part in a fitness session with his teammates at a gym near their Ipanema hotel.
Sneijder was also spared the mobbing of a crowd who followed the players around. Former Liverpool star Dirk Kuyt was surrounded and had to pose to at least 20 selfies before finally being wrestled by security into the gym building.
#WorldCupRank: 13 - Robin van Persie
Van Persie is no stranger to the big stage, but his attacking brilliance must be on full display in order to lift a relatively inexperienced Netherlands side.