Reynolds' agent Todd Eisner made the somber announcement on Thursday. No other details were immediately available.
The legendary actor starred in the Oscar-winning film "Deliverance" in 1972 and the Oscar-nominated "Boogie Nights" in 1997. He also had roles in commercial favorites such as "Smokey and the Bandit" and the hit 1990s TV show "Evening Shade."
Raised in Florida as a football star, Reynolds earned a scholarship to play at Florida State University. However, his dreams of playing professionally ended with a leg injury and car accident. With football behind him, he turned to acting.
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After first being cast in several plays, Reynolds started landing small roles on television. Then came his breakout performance in "Deliverance."
Reynolds became a huge star in the 1970s and 1980s, with his most memorable role as Bo "Bandit" Darville in "Smokey and the Bandit" opposite Sally Field. The two even shared a romance off-screen.
Known as a ladies man, Reynolds also dated Farrah Fawcett, Dinah Shore and Loni Anderson, with whom he adopted a son. But their 5-year marriage came to a bitter end in the tabloids.
Over the years, Reynolds overcame an addiction to prescription drugs. He later bounced back with one of his biggest performances - his role as a pornography director in "Boogie Nights." His performance earned him an Oscar nomination and a Golden Globe.
Reynolds' career spanned more than 50 years. When reflecting on his life, Reynolds once said, "Let me just tell you all. I had a hell of a good time."
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The Associated Press contributed to this report.