The event hasn't been here since 1990. 20,000 people from around the world are expected to attend.
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"One of the things we are doing with this conference to ensure we get a larger number of people participating- young people, young researchers, young activists from all over the world- we will be increasing our scholarships," said Cynthia Carey-Grant, co-chairperson of the conference.
On the front row listening to her remarks were local, state and national politicians including the mayors of Oakland and San Francisco, Congresswoman Barbara Lee and House Speaker Nancy Pelosi.
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Carey-Grant said this is the largest AIDS/HIV conference in the world. It will be held in Oakland and San Francisco from July 6-10, 2020.