On Saturday and Sunday, the Lake Merritt station will be closed and there will be no service between that station and the Fruitvale station, following similar closures on several weekends since April.
There will be free bus shuttles provided for riders between the 19th Street Oakland and Fruitvale stations.
The closure will cause 20- to 40-minute delays in the area, BART officials said.
More information is available on BART's website.