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At 7:04 p.m., at least three vehicles were reported to be on fire on the highway, near the Fremont Boulevard off-ramp, CHP officials said.
At least one vehicle was reported to be fully engulfed in flames.
The incident prompted CHP officers to shut down all northbound lanes at 7:18 p.m. An estimated time for when the highway would reopen was not given.
Stay with ABC7 News for the latest details on this developing story.