The crash happened around 8:30 a.m. and San Jose firefighters and Hazmat teams are on scene.
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The building the car crashed into is where the school stores swimming pool chemicals so there are concerns about the safety of those chemicals.
Crews helped with a vehicle fire and securing the chemicals.
VIDEO: Moment out-of-control car flies through air, slams into house
Video captures moment out-of-control car flies through air, slams into house
The school is on North 2nd Street and East Mission Street, just north of Downtown San Jose.
Police say the driver of the car is injured, but does not have life-threatening injuries.
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School is not in session and no students are on campus.
Stay with ABC7 News for updates on this developing story.