The incident happened just after 8:30 p.m. on the southbound I-680 near King Road.
No one was struck by gunfire, but a 12-year-old girl suffered cuts from shattered glass.
Investigators say a bullet went through the left rear window and out the right front window.
Officials say the shots came from a vehicle traveling alongside, but there are conflicting reports about what kind of vehicle it was.
This shooting follows a deadly shooting on I-680 Monday night.