The fire was reported at 4:40 a.m. at 35 Hazel Ave, fire officials said. That address is the location of a Beltran Tires shop.
Redwood City police issued an alert asking people to avoid the nearby El Camino Real south of Woodside Road because of the fire.
Shortly after 8:15 a.m., police put out an update saying the roadway has reopened.