The crash was first reported around 8:24 p.m. on Highway 1 in Half Moon Bay between Capistrano Road and Coronado Street.
The CHP said the victim was a 74-year-old man from Burlingame. Workers at Sam's Chowder House said the man had been attending a wedding reception at the restaurant.
Traffic in the area was closed while the crash was being investigated.
Drivers were asked to avoid the area. No further details were immediately available.