It happened at about 3:30 p.m. during rush hour traffic.
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The driver had minor injuries. No one else was hurt.
But cars parked along 10th St. between Bryant and Brannan streets were covered in cement.
For car owner Karl Vandyke, it's an unlucky parking spot. Four months ago, city workers were cutting out a eucalyptus tree when the stump fell out of a bin and smashed his car, parked in the very same spot.
"It's tough being in San Francisco," said Vandyke. "Tough working, tough living, tough driving, tough parking."
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But another car owner had a different reaction upon seeing his Tesla covered in cement.
"I was just impressed that something like that could happen," laughed Sage Oliva. "It's wild!"
Crews were able to get the dump truck off the roadway at about 8:50 p.m. Caltrans crews spent hours cleaning up the mess.
A Caltrans superintendent was sent to the scene to check to make sure the highway is structurally sound.