On Tuesday, the governor ordered the state's casinos to shut down for at least 30 days.
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But the mayor says her city should be allowed to stay open for business.
RELATED: Las Vegas casinos, bars closed to slow coronavirus pandemic spread
She says the economy depends on tourism and casinos being open for dining, entertainment, gaming, and sports.
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Democrat Gov. Steve Sisolak ordered a halt on gambling last week in the state, shutting down casinos and other non-essential businesses like bars and movie theaters.
The last time Las Vegas casinos closed was for Pres. John F. Kennedy's funeral on Nov. 25, 1963.
As of Saturday at 6 p.m., there were 190 positive cases in the state and two deaths related to the virus.