The crash was reported at about 9 p.m. near 29th Avenue and East 12th Street. Officers arrived at the scene and found a vehicle several yards away from the intersection.
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According to fire officials, the man was the only person in the vehicle and they attempted to use the Jaws of Life, a rescue tool to free a person inside, however, he was pronounced dead when emergency personnel arrived.
Police blocked northbound traffic along 29th Avenue and southbound traffic at East 12th Street to speak with possible witnesses.
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Stay with ABC7 News for this developing story.