SAN FRANCISCO (KGO) -- Ed Lee is not the first San Francisco mayor to die while serving out his term.
RELATED: San Francisco Mayor Ed Lee passes away at age 65
The last time it happened was in 1978 when the death of then Mayor George Moscone rocked the entire city.
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Their deaths were very different, but what followed could provide some important lessons for new acting mayor London Breed.
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VIDEO: Who is acting San Francisco Mayor London Breed?