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The homeowner's association tells ABC7 News that the homeowner on the 41st floor left the window open, and they think that combined with gale-force winds caused the window to fail.
The fire department responded and reported shattered glass fell onto the street below.
RELATED: $100 million fix proposed for leaning, sinking San Francisco Millennium Tower
Police shut down the intersection of Mission and Fremont street, which has since reopened.
Crews were able to fix the window on Sunday afternoon.
The HOA says a building inspector surveyed the damage and cleared the building.
This is just the latest issue involving Millennium.
The 58-story skyscraper has sunk 17 inches and tilted two inches since it opened in 2009. Then, a window on the 36th floor cracked in 2018.
RELATED: Settlement tentatively reached in lawsuit involving SF Millennium Tower homeowners
Last year, a lawyer for a group of homeowners says a tentative agreement was reached to stabilize the building and compensate residents for the tower's defect.