Briana Villegas, 14, was last seen Friday at 6:30 p.m. She may be in Sunnyvale with family.
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Briana is 5 feet 2 inches tall, 100 pounds with brown hair and brown eyes, according to police. She was last seen wearing black bicycle shorts and a black shirt with the letters "OMI" on it.
Police said Briana is in good physical and mental condition.
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Anyone with information about the girl can call the Police Department's missing persons unit at (510) 238-3641.