Flames ignited at the abandoned building on East 10th Street just before 4:30 a.m. Saturday.
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Video in the media player above is from a previous update
Firefighters posted a photo of a burning building, which appears to be the Enean Theater.
Residents in a home nearby on East 9th Street were ordered to evacuate.
Fire crews were pulled from inside the building after concerns of the structure collapsing.
"This is an abandoned building and due to the concern of collapse we have pulled our personnel out of the building and are in defensive operations," the fire district said, adding a residence at East 9th Street was evacuated by firefighters.
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Fire officials ask people to avoid the area.
No injuries were reported.
Bay City News contributed to this report