Firefighters from the Contra Costa County Fire Protection District and California Highway Patrol officers were called to the scene in the westbound lanes of the highway near Somersville Road at 1:24 p.m., according to fire dispatch records.
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Six ambulances were called to the scene.
CHP spokesman Officer Dan Gilmore said the injuries were all minor.
The crash remains under investigation, he said.
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Westbound lanes were reopened after being closed for a short time.