SKY7 video shows the crowd.
The protest started in the parking lot of the Walmart on Hesperian Boulevard in San Leandro.
The demonstrators are students from six different high schools in San Lorenzo, Hayward, and Berkeley.
MORE: Bay Area demonstrators honor Veterans Affairs ICU nurse Alex Pretti, other victims of ICE
Students could be seen lining Hesperian Boulevard, with some even crossing into traffic.
Some students have also taken over the median, the sidewalk and the front of a Starbucks store.
This comes as tensions are rising nationwide over immigration enforcement tactics, following a second deadly shooting involving federal agents in Minneapolis.
Stay with ABC7 News for the latest details on this developing story.