The crash was reported at about 5 a.m. on southbound Highway 101 south of Sierra Point Parkway, where a bridge railing was damaged by the big-rig, according to the California Highway Patrol.
The crash also knocked a fence onto overhead power lines that knocked out power on the Caltrain tracks in both directions. Power was restored on the northbound track by about 7:50 a.m. and on the southbound side by about 10 a.m., Caltrain spokesperson Dan Lieberman said.
The two right lanes of southbound Highway 101 are expected to remain closed in the area until about 4 p.m. so Caltrans crews can work on the damaged bridge rail, CHP officials said.
No injuries were reported in the crash.