The first report of the collision came in at 2:48 a.m. on I-680 just north of North Capitol Avenue, CHP Officer Peter Van Eckhardt said.
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The collision had closed all northbound lanes until 3:52 a.m. when officials opened one lane.
At least three vehicles were involved in the collision, Van Eckhardt said.
CHP officials issued a Sig-alert at 3:04 a.m. and canceled it at 4:29 a.m.