It's all a part of the zoo's enrichment program.
YouTube video posted by the zoo shows some otters reaching their paws through the cages to play the keyboard, while others sit back and enjoy the show.
And the otters are't the only ones with musical skills. The zoo also tweeted a link to a video showing Orangutan Bonnie playing the xylophone like a pro.
Officials say playing music helps animals work on their sight, touch, and hearing.