Officers responded at 8:44 a.m. to the intersection of Stanyan Street and Parnassus Avenue, near the UCSF Parnassus campus, and found the pedestrian, who was pronounced dead at the scene. His name was not immediately available.
The driver of the vehicle stayed at the scene and investigators do not suspect impairment to be a factor in the collision.
The investigator on the case tells ABC7 News the truck was making a right on Parnassus and didn't see the pedestrian crossing the street.
No other details were released by police about the case.
Anyone with information about the collision is asked to call the SFPD tip line at (415) 575-4444 or to send a tip by text message to TIP411 with SFPD at the start of the message.
ABC7 News contributed to this report.