The fire broke out at a three-story residential complex at 2233 Powell St., according to the San Francisco Fire Department.
One person was rescued from the blaze and was transported to the hospital. A dog was also rescued.
The fire was first reported by the fire department at 2:22 a.m., and firefighters reported the fire was contained at 3:18 a.m.
One person was displaced due to the fire.
The cause of the fire is under investigation.