Lowe was arrested later Saturday night following the hit-and-run collision that killed four and injured six.
RELATED: Hit-and-run suspect arrested after 4 killed, 6 injured on I-80 in San Pablo
The collision was reported at 8:11 p.m. on Interstate Highway 80 at the San Pablo Dam Road off-ramp. The collision involved five vehicles and Lowe allegedly fled the scene, CHP officials said.
The Contra Costa County Sheriff's Department assisted in the arrest.
Lowe was booked into the county jail in Contra Costa County on suspicion of four counts of felony hit-and-run, felony DUI and driving on a suspended license, CHP Officer Matthew Hamer said.