A sign on the door said it would close at the end of the day.
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ABC7 confirmed Sunday morning it would close at 6 p.m.
It's not clear why the location is closing.
MORE: See's Candies factory in South San Francisco cranks up for Christmas
Take a look inside See's Candies in South SF
If you still need to shop for treats there's a store at Market and Sutter Streets.
See's still has three stores in the city.
It makes more than 100 varieties of candies, including peanut brittle and fudge.
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See's Candies is based in the Bay Area, and has been in business for more than 100 years.
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