A sign on the door said it would close at the end of the day.
ABC7 confirmed Sunday morning it would close at 6 p.m.
It's not clear why the location is closing.
MORE: See's Candies factory in South San Francisco cranks up for Christmas
Take a look inside See's Candies in South SF
If you still need to shop for treats there's a store at Market and Sutter Streets.
See's still has three stores in the city.
It makes more than 100 varieties of candies, including peanut brittle and fudge.
See's Candies is based in the Bay Area, and has been in business for more than 100 years.
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