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Lanes in the westbound direction of Interstate Highway 580 on the bridge were shut down at 8:40 p.m. while first responders dealt with the crash. Lanes were reopened just after 11:30 p.m.
CHP initially believed only involved one vehicle was involved, but at 9:15 p.m. said they now believe there were two vehicles.
A full investigation will be carried out to determine exactly what happened, an officer on the scene said.