Beginning today at 10 p.m., Bay Bridge construction will cause Second Street between Bryant and Harrison streets to be closed to traffic, Muni officials said. The street will reopen Sunday at 1:30 p.m. and the 10-Townsend bus line will be affected.
From 1:30 a.m. on Sunday through Monday at 2 a.m., the construction will also shut down Third Street from Bryant Street to Harrison Street.
That closure will affect the inbound 9X-Bayshore line, the outbound 30-Stockton line, the outbound 45-Union line, the outbound 76-Marin Headlands line and the inbound 91-Owl line.
The annual Cherry Blossom Festival and Parade will also cause street closures on both Saturday and Sunday.
From 4 a.m. Saturday through 11 p.m. Sunday, Post Street between Fillmore and Laguna streets and Webster Street between Sutter Street and Geary Boulevard will be closed for the festival.
Sunday's parade is scheduled to begin at Civic Center at 1 p.m.
But before the parade can begin, about 60 groups will gather to prepare for the parade, which will start at Polk and McAllister streets, head north on Polk Street, go west on Post Street to Fillmore and then disband at Steiner Street.
Muni officials said intersections along the parade route will remain open except when the parade passes through.
The 2-Clement, 3-Jackson, 5-Fulton, 19-Polk, 21-Hayes, 22-Fillmore, 31-Balboa, 38-Geary, 47-Van Ness, 49-Van Ness/Mission and 76-Marin Headlands lines will be affected by the parade.
Another festival and parade, this time honoring Cesar Chavez on Saturday, will begin at 10 a.m. at 24th Street between Bryant Street and Potrero Avenue. The parade itself will start at noon and will travel on 24th Street to Mission Street, head north on Mission Street, turn east on 22nd Street and go south on Folsom Street.
The festival will then be held at the Cesar Chavez Elementary School. The streets will reopen to traffic as the parade passes, according to Muni.
The 12-Folsom, 14-Mission, 14L-Mission, 48-Quintara, 49-Mission/Van Ness and 67-Bernal Heights bus lines will be affected by the parade.
Lastly, on Sunday, the Zippy 5K Run will be held in Golden Gate Park, beginning at 8:30 a.m. on John F. Kennedy Drive by the Conservatory of Flowers. The race will head west by Stow Lake and then return back to the starting point by 10 a.m.
The run will affect the 44-O'Shaugnessy line.
Muni officials encourage event participants and those planning on using Muni bus lines or driving in the city to go to http://www.sfmta.com or call 311.