The incident began shortly after 3:30 a.m. when a big rig was rear-ended by a Honda vehicle traveling in one of the right lanes of Highway 880 just north of Industrial Parkway, Tagle said.
The Honda was disabled and its lights were blacked out due to the initial collision, according to Tagle.
Minutes later, a UPS big rig, whose driver did not see the blacked out Honda, collided with the disabled vehicle, Tagle said.
Both big rigs pulled over to the right hand shoulder, and someone spotted a body laying in a lane of the highway, according to Tagle, who said it was not clear if the man was ejected from the vehicle or if he was already standing outside of it.
The victim has been identified, but his name is not being released pending notification of next of kin, according to the Alameda County coroner's bureau.
Neither of the big rig drivers were injured in the incident, Tagle said.
The three right lanes of Highway 880 were blocked for about two hours at Industrial Parkway because of the collisions, which also caused a small fuel spill, according to CHP Officer Marc Johnston.
A Sig-alert was issued at about 4:25 a.m., and was canceled at about 6:10 a.m. when the lanes were reopened, CHP Officer Ralph Caggiano said.