Mike Shumann has a preview of the opener, and there's no doubt about the emotional readiness of their leader - Head Coach Mike Singletary.
"There's not enough room around here to show you what my emotions are. I'm very excited," said Singletary.
This 49er team will go as far as running back Frank Gore can carry them and when he was told that he said "I was like a little kid, now we get the opportunity first game against the NFC champs, they are going to have their swagger on their backs, but you know, I'm excited for it."
Quarterback Shaun Hill will start the first regular season opener in his eight year career.
"This isn't a time to stop and smell the roses. We have a lot of work to get done. It doesn't stop here," said Hill.
Cornerback Nate Clements has his hands full with the best receiver in football -- Larry Fitzgerald.
"His size, jumping ability, actually his hands as well, so it's going to be a challenge," said Clements.
Speaking of receivers, 49er tight end Vernon Davis is hoping to finally have his break out year.
"The more opportunity you get, the better you can excel at something. I've got to capitalize and take advantage of it," said Davis.
Oh yea, what about Michael Crabtree?
"We're moving forward with people we have," said Hill.
There's a 1:15 p.m. Pacific Time kickoff on Sunday.