Several shots were detected on the Richmond Police Department's Shot Spotter alert system at about 12:55 a.m. Saturday in the 100 block of Third Street, Lt. George Garcia said.
A woman and a man were found inside the home with gunshot wounds. They were taken to an area hospital with life-threatening injuries.
The shots are believed to have been fired from the street, Garcia said.
Witnesses reported seeing a vehicle leave the area following the shooting, but no description of the vehicle or its occupants was reported.