Officers responded to reports of a man down in the 2200 block of Dumbarton Avenue at 7:17 p.m., Sgt. Jeff Liu said.
Police found a 19-year-old man suffering from a gunshot wound, Liu said.
Paramedics rendered aid to the victim who succumbed to his injuries at the scene, he said.
The victim was identified as Josue Barbosa Zamora of East Palo Alto, Liu said.
Anyone with information on this incident is asked to contact East Palo Alto police at (650) 321-1112 or anonymously at (650) 409-6792. Anonymous emails can be sent to epatipnow.org.