The crash was reported around 10:40 a.m. on northbound Highway 17 in the area of the Laurel Curve in Los Gatos, according to the CHP.
No injuries were reported, but all lanes were blocked as of 11:05 a.m. as crews arrived to retrieve the overturned vehicle, according to the CHP.
An estimate for the roadway reopening was not available.
Motorists are advised to expect delays and avoid the area if possible.