Members of Galeria de la Raza hung up a mural at 24th and Bryant streets. It shows two Latino men holding each other and two women, face to face.
It's a copy of the original mural, which was vandalized a few weeks ago.
The artists say intolerance did not disappear with Friday's decision.
"We're talking about the silencing, the discrimination, the hate. Those things are not going away yet. Those things are still very alive in certain communities," artist Ani Rivera said.
A donor who paid for the mural replacement gave the gallery enough money to keep replacing it if it gets vandalized again.